Nature, Body & Extraordinary Life
Body Systems & Human Adaptation
Collection
The gut-brain axis is real. The marketing claims built around it are often much stronger than the evidence.
4 Articles
ARTICLES
01
The gut-brain axis is real, bidirectional and biologically complex. Learn how nerves, immune signals, hormones and microbial metabolites connect the gut and brain.
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Human studies link the gut microbiome with depression and anxiety, but association is not causation. Here is what the evidence actually supports.
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Some randomized trials suggest probiotic benefits for depression or anxiety, but effects differ by strain, population and outcome measure. The evidence needs precision.
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Emeran Mayer's 2016 book helped popularize the brain-gut-microbiome network. A decade later, the core idea holds up, while several therapeutic claims still need caution.
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